At the close in Tokyo, the Nikkei 225 lost 1.57%.
The best performers of the session on the Nikkei 225 were Chugai Pharmaceutical Co., Ltd. (T:4519), which rose 6.94% or 805.0 points to trade at 12405.0 at the close. Meanwhile, Fujifilm Holdings Corp. (T:4901) added 5.98% or 300.0 points to end at 5320.0 and Teijin Ltd. (T:3401) was up 4.97% or 90.0 points to 1900.0 in late trade.
The worst performers of the session were ANA Holdings Inc (T:9202), which fell 9.97% or 299.0 points to trade at 2700.0 at the close. IHI Corp. (T:7013) declined 7.91% or 113.0 points to end at 1316.0 and Nippon Sheet Glass Co., Ltd. (T:5202) was down 6.99% or 26.0 points to 346.0.
Falling stocks outnumbered advancing ones on the Tokyo Stock Exchange by 2874 to 845 and 85 ended unchanged.
Shares in Chugai Pharmaceutical Co., Ltd. (T:4519) rose to all time highs; gaining 6.94% or 805.0 to 12405.0.
The Nikkei Volatility, which measures the implied volatility of Nikkei 225 options, was unchanged 0.00% to 52.78.
Crude oil for May delivery was down 5.53% or 1.19 to $20.32 a barrel. Elsewhere in commodities trading, Brent oil for delivery in June fell 5.83% or 1.63 to hit $26.32 a barrel, while the June Gold Futures contract fell 0.44% or 7.25 to trade at $1646.85 a troy ounce.
USD/JPY was up 0.13% to 108.03, while EUR/JPY fell 0.53% to 119.60.
The US Dollar Index Futures was up 0.48% at 99.013.